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Sonodynamic therapy-induced foam cells apoptosis activates the phagocytic PPARγ-LXRα-ABCA1/ABCG1 pathway and promotes cholesterol efflux in advanced plaque

In advanced atherosclerotic plaques, defective efferocytosis of apoptotic foam cells and decreased cholesterol efflux contribute to lesion progression. In our previous study, we demonstrated that 5-aminolevulinic acid (ALA)-mediated sonodynamic therapy (SDT) could induce foam cells apoptosis via the...

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Detalles Bibliográficos
Autores principales: Wang, Huan, Yang, Yang, Sun, Xin, Tian, Fang, Guo, Shuyuan, Wang, Wei, Tian, Zhen, Jin, Hong, Zhang, Zhiguo, Tian, Ye
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6217053/
https://www.ncbi.nlm.nih.gov/pubmed/30429880
http://dx.doi.org/10.7150/thno.26193