Enhanced bioreduction-responsive diselenide-based dimeric prodrug nanoparticles for triple negative breast cancer therapy

Efficient drug accumulation in tumor is essential for chemotherapy. We developed redox-responsive diselenide-based high-loading prodrug nanoparticles (NPs) for targeted triple negative breast cancer (TNBC) treatment. Method: Redox-responsive diselenide bond (Se-Se) containing dimeric prodrug (PTXD-S...

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Detalles Bibliográficos
Autores principales: He, Xi, Zhang, Jinxiao, Li, Chao, Zhang, Yu, Lu, Yifei, Zhang, Yujie, Liu, Lisha, Ruan, Chunhui, Chen, Qinjun, Chen, Xinli, Guo, Qin, Sun, Tao, Cheng, Jianjun, Jiang, Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6217054/
https://www.ncbi.nlm.nih.gov/pubmed/30429875
http://dx.doi.org/10.7150/thno.27581

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