Blood exosomes regulate the tissue distribution of grapefruit-derived nanovector via CD36 and IGFR1 pathways

Tumor-specific delivery of therapeutics is challenging. One of the major hurdles for successfully delivering targeted agents by nanovectors is the filtering role of the liver in rapidly sequestering nanovectors from the circulation. Exosomes, a type of endogenous nanoparticle, circulate continuously...

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Detalles Bibliográficos
Autores principales: Wang, Qi-long, Zhuang, XiaoYing, Sriwastva, Mukesh K., Mu, Jingyao, Teng, Yun, Deng, Zhongbin, Zhang, Lifeng, Sundaram, Kumaran, Kumar, Anil, Miller, Donald, Yan, Jun, Zhang, Huang-Ge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6217058/
https://www.ncbi.nlm.nih.gov/pubmed/30429877
http://dx.doi.org/10.7150/thno.27608

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