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16-Hydroxycleroda-3,13-dien-15,16-olide induces anoikis in human renal cell carcinoma cells: involvement of focal adhesion disassembly and signaling

BACKGROUND: Clerodane diterpene, 16-hydroxycleroda-3,13-dien-15,16-olide (CD) isolated from Polyalthia longifolia Benth. & Hook. f. var. pendula was found to be a potential apoptotic inducer in human leukemia, lung cancer, and colon cancer cells. However, the molecular mechanism remains elusive...

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Detalles Bibliográficos
Autores principales:	Chen, Yu-Chi, Huang, Bu-Miin, Lee, Wei-Chang, Chen, Yung-Chia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2018
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6217210/ https://www.ncbi.nlm.nih.gov/pubmed/30464516 http://dx.doi.org/10.2147/OTT.S173378

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