Shift from androgen to estrogen action causes abdominal muscle fibrosis, atrophy, and inguinal hernia in a transgenic male mouse model

Inguinal hernia develops primarily in elderly men, and more than one in four men will undergo inguinal hernia repair during their lifetime. However, the underlying mechanisms behind hernia formation remain unknown. It is known that testosterone and estradiol can regulate skeletal muscle mass. We her...

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Detalles Bibliográficos
Autores principales: Zhao, Hong, Zhou, Ling, Li, Lin, Coon V, John, Chatterton, Robert T., Brooks, David C., Jiang, Enze, Liu, Li, Xu, Xia, Dong, Zhiyong, DeMayo, Francesco J., Stulberg, Jonah J., Tourtellotte, Warren G., Bulun, Serdar E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2018
Materias:
PNAS Plus
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6217386/
https://www.ncbi.nlm.nih.gov/pubmed/30327348
http://dx.doi.org/10.1073/pnas.1807765115

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6217386/
https://www.ncbi.nlm.nih.gov/pubmed/30327348
http://dx.doi.org/10.1073/pnas.1807765115

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