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Shift from androgen to estrogen action causes abdominal muscle fibrosis, atrophy, and inguinal hernia in a transgenic male mouse model
Inguinal hernia develops primarily in elderly men, and more than one in four men will undergo inguinal hernia repair during their lifetime. However, the underlying mechanisms behind hernia formation remain unknown. It is known that testosterone and estradiol can regulate skeletal muscle mass. We her...
Autores principales: | Zhao, Hong, Zhou, Ling, Li, Lin, Coon V, John, Chatterton, Robert T., Brooks, David C., Jiang, Enze, Liu, Li, Xu, Xia, Dong, Zhiyong, DeMayo, Francesco J., Stulberg, Jonah J., Tourtellotte, Warren G., Bulun, Serdar E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6217386/ https://www.ncbi.nlm.nih.gov/pubmed/30327348 http://dx.doi.org/10.1073/pnas.1807765115 |
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