Molecular profiling of nonalcoholic fatty liver disease-associated hepatocellular carcinoma using SB transposon mutagenesis

Nonalcoholic fatty liver disease (NAFLD) is the fastest rising cause of hepatocellular carcinoma (HCC) in Western countries; however, the molecular mechanisms that cause NAFLD-HCC remain elusive. To identify molecular drivers of NAFLD-HCC, we performed Sleeping Beauty (SB) transposon mutagenesis scr...

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Detalles Bibliográficos
Autores principales: Kodama, Takahiro, Yi, Jing, Newberg, Justin Y., Tien, Jean C., Wu, Hao, Finegold, Milton J., Kodama, Michiko, Wei, Zhubo, Tamura, Takeshi, Takehara, Tetsuo, Johnson, Randy L., Jenkins, Nancy A., Copeland, Neal G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2018
Materias:
PNAS Plus
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6217425/
https://www.ncbi.nlm.nih.gov/pubmed/30327349
http://dx.doi.org/10.1073/pnas.1808968115

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