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Frequent monoallelic or skewed expression for developmental genes in CNS-derived cells and evidence for balancing selection
Cellular mosaicism due to monoallelic autosomal expression (MAE), with cell selection during development, is becoming increasingly recognized as prevalent in mammals, leading to interest in understanding its extent and mechanism(s). We report here use of clonal cell lines derived from the CNS of adu...
Autores principales: | Branciamore, Sergio, Valo, Zuzana, Li, Min, Wang, Jinhui, Riggs, Arthur D., Singer-Sam, Judith |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6217436/ https://www.ncbi.nlm.nih.gov/pubmed/30322913 http://dx.doi.org/10.1073/pnas.1808652115 |
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