The Symmetric Tetravalent Sulfhydryl-Specific Linker NATBA Facilitates a Combinatorial “Tool Kit” Strategy for Phage Display-Based Selection of Functionalized Bicyclic Peptides

[Image: see text] The rigid conformation of constrained bicyclic peptides provides a number of advantages over larger protein-based ligands, including better chemical stability, enhanced tissue penetration, and a wider field of possible applications. Selective chemical modification strategies are ab...

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Detalles Bibliográficos
Autores principales: Ernst, Christoph, Sindlinger, Julia, Schwarzer, Dirk, Koch, Pierre, Boeckler, Frank M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6217522/
https://www.ncbi.nlm.nih.gov/pubmed/30411004
http://dx.doi.org/10.1021/acsomega.8b01814

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