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Refining the structure−activity relationships of 2-phenylcyclopropane carboxylic acids as inhibitors of O-acetylserine sulfhydrylase isoforms

The lack of efficacy of current antibacterials to treat multidrug resistant bacteria poses a life-threatening alarm. In order to develop enhancers of the antibacterial activity, we carried out a medicinal chemistry campaign aiming to develop inhibitors of enzymes that synthesise cysteine and belong...

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Detalles Bibliográficos
Autores principales:	Magalhães, Joana, Franko, Nina, Annunziato, Giannamaria, Pieroni, Marco, Benoni, Roberto, Nikitjuka, Anna, Mozzarelli, Andrea, Bettati, Stefano, Karawajczyk, Anna, Jirgensons, Aigars, Campanini, Barbara, Costantino, Gabriele
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2018
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6217552/ https://www.ncbi.nlm.nih.gov/pubmed/30362368 http://dx.doi.org/10.1080/14756366.2018.1518959

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