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Exosomal miR-99a-5p is elevated in sera of ovarian cancer patients and promotes cancer cell invasion by increasing fibronectin and vitronectin expression in neighboring peritoneal mesothelial cells
BACKGROUND: microRNAs (miRNAs) stably exist in circulating blood and are encapsulated in extracellular vesicles such as exosomes. The aims of this study were to identify which exosomal miRNAs are highly produced from epithelial ovarian cancer (EOC) cells, to analyze whether serum miRNA can be used t...
Autores principales: | Yoshimura, Akihiko, Sawada, Kenjiro, Nakamura, Koji, Kinose, Yasuto, Nakatsuka, Erika, Kobayashi, Masaki, Miyamoto, Mayuko, Ishida, Kyoso, Matsumoto, Yuri, Kodama, Michiko, Hashimoto, Kae, Mabuchi, Seiji, Kimura, Tadashi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6217763/ https://www.ncbi.nlm.nih.gov/pubmed/30396333 http://dx.doi.org/10.1186/s12885-018-4974-5 |
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