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Direct conversion of mouse astrocytes into neural progenitor cells and specific lineages of neurons

BACKGROUND: Cell replacement therapy has been envisioned as a promising treatment for neurodegenerative diseases. Due to the ethical concerns of ESCs-derived neural progenitor cells (NPCs) and tumorigenic potential of iPSCs, reprogramming of somatic cells directly into multipotent NPCs has emerged a...

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Detalles Bibliográficos
Autores principales:	Ma, Kangmu, Deng, Xiaobei, Xia, Xiaohuan, Fan, Zhaohuan, Qi, Xinrui, Wang, Yongxiang, Li, Yuju, Ma, Yizhao, Chen, Qiang, Peng, Hui, Ding, Jianqing, Li, Chunhong, Huang, Yunlong, Tian, Changhai, Zheng, Jialin C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6217767/ https://www.ncbi.nlm.nih.gov/pubmed/30410751 http://dx.doi.org/10.1186/s40035-018-0132-x

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