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An agent-based model for drug-radiation interactions in the tumour microenvironment: Hypoxia-activated prodrug SN30000 in multicellular tumour spheroids

Multicellular tumour spheroids capture many characteristics of human tumour microenvironments, including hypoxia, and represent an experimentally tractable in vitro model for studying interactions between radiotherapy and anticancer drugs. However, interpreting spheroid data is challenging because o...

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Detalles Bibliográficos
Autores principales:	Mao, Xinjian, McManaway, Sarah, Jaiswal, Jagdish K., Patel, Priyanka B., Wilson, William R., Hicks, Kevin O., Bogle, Gib
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6218095/ https://www.ncbi.nlm.nih.gov/pubmed/30356233 http://dx.doi.org/10.1371/journal.pcbi.1006469

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