“Of Mice and Measures”: A Project to Improve How We Advance Duchenne Muscular Dystrophy Therapies to the Clinic: First Workshop Report: Examining current findings and opportunities around the emerging D2.B10-Dmd(mdx)/J (D2/mdx) model in context of the classic C57BL/10ScSn-Dmd(mdx)/J (Bl10/mdx)

A new line of dystrophic mdx mice on the DBA/2J (D2) background has emerged as a candidate to study the efficacy of therapeutic approaches for Duchenne muscular dystrophy (DMD). These mice harbor genetic polymorphisms that appear to increase the severity of the dystropathology, with disease modifier...

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Detalles Bibliográficos
Autores principales: Gordish-Dressman, Heather, Willmann, Raffaella, Dalle Pazze, Laura, Kreibich, Arati, van Putten, Maaike, Heydemann, Ahlke, Bogdanik, Laurent, Lutz, Cathleen, Davies, Kay, Demonbreun, Alexis R., Duan, Dongsheng, Elsey, David, Fukada, So-ichiro, Girgenrath, Mahasweta, Patrick Gonzalez, J., Grounds, Miranda D., Nichols, Andy, Partridge, Terry, Passini, Marco, Sanarica, Francesca, Schnell, Frederick J., Wells, Dominic J., Yokota, Toshifumi, Young, Courtney S., Zhong, Zhong, Spurney, Christopher, Spencer, Melissa, De Luca, Annamaria, Nagaraju, Kanneboyina, Aartsma-Rus, Annemieke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6218134/
https://www.ncbi.nlm.nih.gov/pubmed/30198876
http://dx.doi.org/10.3233/JND-180324

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