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High-throughput DNA Sequencing Identifies Novel CtIP (RBBP8) Variants in Muscle-invasive Bladder Cancer Patients

BACKGROUND: Germline mutations in DNA damage signalling and repair genes predispose individuals to cancer. Rare germline variants may also increase cancer risk and be predictive of outcomes following cancer treatments, but require high-throughput sequencing (HTS) for detection in large cohorts. OBJE...

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Detalles Bibliográficos
Autores principales:	Jevons, Sarah J., Green, Angela, Lunter, Gerton, Kartsonaki, Christiana, Buck, David, Piazza, Paolo, Kiltie, Anne E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	IOS Press 2015
Materias:	Research Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6218178/ https://www.ncbi.nlm.nih.gov/pubmed/30561437 http://dx.doi.org/10.3233/BLC-150007

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