The Developmental Shift of NMDA Receptor Composition Proceeds Independently of GluN2 Subunit-Specific GluN2 C-Terminal Sequences

The GluN2 subtype (2A versus 2B) determines biophysical properties and signaling of forebrain NMDA receptors (NMDARs). During development, GluN2A becomes incorporated into previously GluN2B-dominated NMDARs. This “switch” is proposed to be driven by distinct features of GluN2 cytoplasmic C-terminal...

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Detalles Bibliográficos
Autores principales: McKay, Sean, Ryan, Tomás J., McQueen, Jamie, Indersmitten, Tim, Marwick, Katie F.M., Hasel, Philip, Kopanitsa, Maksym V., Baxter, Paul S., Martel, Marc-André, Kind, Peter C., Wyllie, David J.A., O’Dell, Thomas J., Grant, Seth G.N., Hardingham, Giles E., Komiyama, Noboru H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6218242/
https://www.ncbi.nlm.nih.gov/pubmed/30355491
http://dx.doi.org/10.1016/j.celrep.2018.09.089

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