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Dual androgen receptor (AR) and STAT3 inhibition by a compound targeting the AR amino‐terminal domain

Prostate cancer (PCa) often recurs as incurable castration‐resistant prostate cancer (CRPC) after the failure of androgen deprivation therapy. CRPC development relies on androgen receptor (AR) signaling. The IL6/STAT3 pathway is also a key driver of CRPC. The crosstalk between IL6/STAT3 and the AR p...

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Detalles Bibliográficos
Autores principales:	Hua, Yaping, Azeem, Waqas, Shen, Yunheng, Zhang, Shoude, Olsen, Jan R., Øyan, Anne M., Ke, Xisong, Zhang, Weidong, Kalland, Karl‐Henning
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2018
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6218398/ https://www.ncbi.nlm.nih.gov/pubmed/30410767 http://dx.doi.org/10.1002/prp2.437

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