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METTL3-mediated N(6)-methyladenosine mRNA modification enhances long-term memory consolidation
The formation of long-term memory is critical for learning ability and social behaviors of humans and animals, yet its underlying mechanisms are largely unknown. We found that the efficacy of hippocampus-dependent memory consolidation is regulated by METTL3, an RNA N(6)-methyladenosine (m(6)A) methy...
Autores principales: | Zhang, Zeyu, Wang, Meng, Xie, Dongfang, Huang, Zenghui, Zhang, Lisha, Yang, Ying, Ma, Dongxue, Li, Wenguang, Zhou, Qi, Yang, Yun-Gui, Wang, Xiu-Jie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6218447/ https://www.ncbi.nlm.nih.gov/pubmed/30297870 http://dx.doi.org/10.1038/s41422-018-0092-9 |
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