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Genetic background and window of exposure contribute to thyroid dysfunction promoted by low-dose exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin in mice

Genetic and environmental factors contribute to thyroid diseases. Although still debated, 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) is thought to induce thyroid dysfunction in humans and rodents. The data here reported point out the contribution of the exposure window and genetic background in medi...

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Detalles Bibliográficos
Autores principales: Reale, Carla, Porreca, Immacolata, Russo, Filomena, Marotta, Maria, Roberto, Luca, Russo, Nicola Antonino, Carchia, Emanuele, Mallardo, Massimo, De Felice, Mario, Ambrosino, Concetta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6218492/
https://www.ncbi.nlm.nih.gov/pubmed/30397221
http://dx.doi.org/10.1038/s41598-018-34427-2