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Diversity and convergence of mechanisms involved in pyrethroid resistance in the stored grain weevils, Sitophilus spp.

Target-site mutations and changes in insect metabolism or behavior are common mechanisms in insecticide-resistant insects. The co-occurrence of such mechanisms in a pest strain is a prominent threat to their management, particularly when alternative compounds are scarce. Pyrethroid resistance among...

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Autores principales: Haddi, Khalid, Valbon, Wilson R., Viteri Jumbo, Luis O., de Oliveira, Luiz O., Guedes, Raul N. C., Oliveira, Eugenio E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6218525/
https://www.ncbi.nlm.nih.gov/pubmed/30397209
http://dx.doi.org/10.1038/s41598-018-34513-5
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author Haddi, Khalid
Valbon, Wilson R.
Viteri Jumbo, Luis O.
de Oliveira, Luiz O.
Guedes, Raul N. C.
Oliveira, Eugenio E.
author_facet Haddi, Khalid
Valbon, Wilson R.
Viteri Jumbo, Luis O.
de Oliveira, Luiz O.
Guedes, Raul N. C.
Oliveira, Eugenio E.
author_sort Haddi, Khalid
collection PubMed
description Target-site mutations and changes in insect metabolism or behavior are common mechanisms in insecticide-resistant insects. The co-occurrence of such mechanisms in a pest strain is a prominent threat to their management, particularly when alternative compounds are scarce. Pyrethroid resistance among stored grain weevils (i.e., Sitophilus spp.) is an example of a long-standing concern, for which reports of resistance generally focus on a single mechanism in a single species. Here, we investigated pyrethroid resistance in maize and rice weevils (i.e., Sitophilus zeamais and S. oryzae), exploring potential knockdown resistance (kdr) mutations in their sodium channels (primary site for pyrethroid actions) and potential changes in their detoxification and walking processes. Resistance in pyrethroid-resistant rice weevils was associated with the combination of a kdr mutation (L1014F) and increases in walking and detoxification activities, while another kdr mutation (T929I) combined with increases in walking activity were the primary pyrethroid resistance mechanisms in maize weevils. Our results suggest that the selection of pyrethroid-resistant individuals in these weevil species may result from multiple and differential mechanisms because the L1014F mutation was only detected in Latin American rice weevils (e.g., Brazil, Argentina and Uruguay), not in Australian and Turkish rice weevils or Brazilian maize weevils.
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spelling pubmed-62185252018-11-07 Diversity and convergence of mechanisms involved in pyrethroid resistance in the stored grain weevils, Sitophilus spp. Haddi, Khalid Valbon, Wilson R. Viteri Jumbo, Luis O. de Oliveira, Luiz O. Guedes, Raul N. C. Oliveira, Eugenio E. Sci Rep Article Target-site mutations and changes in insect metabolism or behavior are common mechanisms in insecticide-resistant insects. The co-occurrence of such mechanisms in a pest strain is a prominent threat to their management, particularly when alternative compounds are scarce. Pyrethroid resistance among stored grain weevils (i.e., Sitophilus spp.) is an example of a long-standing concern, for which reports of resistance generally focus on a single mechanism in a single species. Here, we investigated pyrethroid resistance in maize and rice weevils (i.e., Sitophilus zeamais and S. oryzae), exploring potential knockdown resistance (kdr) mutations in their sodium channels (primary site for pyrethroid actions) and potential changes in their detoxification and walking processes. Resistance in pyrethroid-resistant rice weevils was associated with the combination of a kdr mutation (L1014F) and increases in walking and detoxification activities, while another kdr mutation (T929I) combined with increases in walking activity were the primary pyrethroid resistance mechanisms in maize weevils. Our results suggest that the selection of pyrethroid-resistant individuals in these weevil species may result from multiple and differential mechanisms because the L1014F mutation was only detected in Latin American rice weevils (e.g., Brazil, Argentina and Uruguay), not in Australian and Turkish rice weevils or Brazilian maize weevils. Nature Publishing Group UK 2018-11-05 /pmc/articles/PMC6218525/ /pubmed/30397209 http://dx.doi.org/10.1038/s41598-018-34513-5 Text en © The Author(s) 2018 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Haddi, Khalid
Valbon, Wilson R.
Viteri Jumbo, Luis O.
de Oliveira, Luiz O.
Guedes, Raul N. C.
Oliveira, Eugenio E.
Diversity and convergence of mechanisms involved in pyrethroid resistance in the stored grain weevils, Sitophilus spp.
title Diversity and convergence of mechanisms involved in pyrethroid resistance in the stored grain weevils, Sitophilus spp.
title_full Diversity and convergence of mechanisms involved in pyrethroid resistance in the stored grain weevils, Sitophilus spp.
title_fullStr Diversity and convergence of mechanisms involved in pyrethroid resistance in the stored grain weevils, Sitophilus spp.
title_full_unstemmed Diversity and convergence of mechanisms involved in pyrethroid resistance in the stored grain weevils, Sitophilus spp.
title_short Diversity and convergence of mechanisms involved in pyrethroid resistance in the stored grain weevils, Sitophilus spp.
title_sort diversity and convergence of mechanisms involved in pyrethroid resistance in the stored grain weevils, sitophilus spp.
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6218525/
https://www.ncbi.nlm.nih.gov/pubmed/30397209
http://dx.doi.org/10.1038/s41598-018-34513-5
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