Genetic variation determines VEGF-A plasma levels in cancer patients

Angiogenesis is essential in tumor biology and is regulated by vascular endothelial growth factor (VEGF) ligands and receptors. Here we aimed to discover genetic variants associated with levels of circulating angiogenic proteins in cancer patients. Plasma was collected at baseline in 216 pancreatic...

Descripción completa

Detalles Bibliográficos
Autores principales: Innocenti, Federico, Jiang, Chen, Sibley, Alexander B., Etheridge, Amy S., Hatch, Ace J., Denning, Stefanie, Niedzwiecki, Donna, Shterev, Ivo D., Lin, Jiaxing, Furukawa, Yoichi, Kubo, Michiaki, Kindler, Hedy L., Auman, J. Todd, Venook, Alan P., Hurwitz, Herbert I., McLeod, Howard L., Ratain, Mark J., Gordan, Raluca, Nixon, Andrew B., Owzar, Kouros
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6218528/
https://www.ncbi.nlm.nih.gov/pubmed/30397360
http://dx.doi.org/10.1038/s41598-018-34506-4

Ejemplares similares

Ejemplares similares