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Stent graft coverage of dual-stent strategy in the management of abdominal aortic aneurysms

Treating an abdominal aortic aneurysm (AAA) with a stent graft (SG) and a multilayer stent (MS) is a key technology in isolating flow fields. Clinically, dual stents (an SG in the proximal and an MS in the distal of AAA) are used for treatment of AAA, but only a few studies have examined the relatio...

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Autores principales: Ding, Yuan, Zhongyou, Li, Wentao, Jiang, Yinci, Zhang, Zhenze, Wang, Yu, Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6218544/
https://www.ncbi.nlm.nih.gov/pubmed/30397213
http://dx.doi.org/10.1038/s41598-018-34354-2
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author Ding, Yuan
Zhongyou, Li
Wentao, Jiang
Yinci, Zhang
Zhenze, Wang
Yu, Chen
author_facet Ding, Yuan
Zhongyou, Li
Wentao, Jiang
Yinci, Zhang
Zhenze, Wang
Yu, Chen
author_sort Ding, Yuan
collection PubMed
description Treating an abdominal aortic aneurysm (AAA) with a stent graft (SG) and a multilayer stent (MS) is a key technology in isolating flow fields. Clinically, dual stents (an SG in the proximal and an MS in the distal of AAA) are used for treatment of AAA, but only a few studies have examined the relationship between SG coverage and treatment effects. Through numerical simulation of the hemodynamics after SG and MS implantation, the SG coverage and position were simulated at 0% (0 mm), 25% (13.75 mm), 50% (27.5 mm), and 75% (41.25 mm). With increasing SG coverage, the pressure on the aneurysm sac wall and the flow of branch vessels gradually decreased, and the lower wall shear stress (WSS) gradually increased. The changes in pressure, lower WSS, and the mass flow rate of the branch vessels did not change significantly. The coverage of the SG has a nonsignificant effect on hemodynamics in the treatment of AAA; the implantation position need not be very precise. This research can provide theoretic support for clinicians’ decision-making.
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spelling pubmed-62185442018-11-07 Stent graft coverage of dual-stent strategy in the management of abdominal aortic aneurysms Ding, Yuan Zhongyou, Li Wentao, Jiang Yinci, Zhang Zhenze, Wang Yu, Chen Sci Rep Article Treating an abdominal aortic aneurysm (AAA) with a stent graft (SG) and a multilayer stent (MS) is a key technology in isolating flow fields. Clinically, dual stents (an SG in the proximal and an MS in the distal of AAA) are used for treatment of AAA, but only a few studies have examined the relationship between SG coverage and treatment effects. Through numerical simulation of the hemodynamics after SG and MS implantation, the SG coverage and position were simulated at 0% (0 mm), 25% (13.75 mm), 50% (27.5 mm), and 75% (41.25 mm). With increasing SG coverage, the pressure on the aneurysm sac wall and the flow of branch vessels gradually decreased, and the lower wall shear stress (WSS) gradually increased. The changes in pressure, lower WSS, and the mass flow rate of the branch vessels did not change significantly. The coverage of the SG has a nonsignificant effect on hemodynamics in the treatment of AAA; the implantation position need not be very precise. This research can provide theoretic support for clinicians’ decision-making. Nature Publishing Group UK 2018-11-05 /pmc/articles/PMC6218544/ /pubmed/30397213 http://dx.doi.org/10.1038/s41598-018-34354-2 Text en © The Author(s) 2018 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Ding, Yuan
Zhongyou, Li
Wentao, Jiang
Yinci, Zhang
Zhenze, Wang
Yu, Chen
Stent graft coverage of dual-stent strategy in the management of abdominal aortic aneurysms
title Stent graft coverage of dual-stent strategy in the management of abdominal aortic aneurysms
title_full Stent graft coverage of dual-stent strategy in the management of abdominal aortic aneurysms
title_fullStr Stent graft coverage of dual-stent strategy in the management of abdominal aortic aneurysms
title_full_unstemmed Stent graft coverage of dual-stent strategy in the management of abdominal aortic aneurysms
title_short Stent graft coverage of dual-stent strategy in the management of abdominal aortic aneurysms
title_sort stent graft coverage of dual-stent strategy in the management of abdominal aortic aneurysms
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6218544/
https://www.ncbi.nlm.nih.gov/pubmed/30397213
http://dx.doi.org/10.1038/s41598-018-34354-2
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