Cargando…
Stent graft coverage of dual-stent strategy in the management of abdominal aortic aneurysms
Treating an abdominal aortic aneurysm (AAA) with a stent graft (SG) and a multilayer stent (MS) is a key technology in isolating flow fields. Clinically, dual stents (an SG in the proximal and an MS in the distal of AAA) are used for treatment of AAA, but only a few studies have examined the relatio...
Autores principales: | , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6218544/ https://www.ncbi.nlm.nih.gov/pubmed/30397213 http://dx.doi.org/10.1038/s41598-018-34354-2 |
_version_ | 1783368476763619328 |
---|---|
author | Ding, Yuan Zhongyou, Li Wentao, Jiang Yinci, Zhang Zhenze, Wang Yu, Chen |
author_facet | Ding, Yuan Zhongyou, Li Wentao, Jiang Yinci, Zhang Zhenze, Wang Yu, Chen |
author_sort | Ding, Yuan |
collection | PubMed |
description | Treating an abdominal aortic aneurysm (AAA) with a stent graft (SG) and a multilayer stent (MS) is a key technology in isolating flow fields. Clinically, dual stents (an SG in the proximal and an MS in the distal of AAA) are used for treatment of AAA, but only a few studies have examined the relationship between SG coverage and treatment effects. Through numerical simulation of the hemodynamics after SG and MS implantation, the SG coverage and position were simulated at 0% (0 mm), 25% (13.75 mm), 50% (27.5 mm), and 75% (41.25 mm). With increasing SG coverage, the pressure on the aneurysm sac wall and the flow of branch vessels gradually decreased, and the lower wall shear stress (WSS) gradually increased. The changes in pressure, lower WSS, and the mass flow rate of the branch vessels did not change significantly. The coverage of the SG has a nonsignificant effect on hemodynamics in the treatment of AAA; the implantation position need not be very precise. This research can provide theoretic support for clinicians’ decision-making. |
format | Online Article Text |
id | pubmed-6218544 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-62185442018-11-07 Stent graft coverage of dual-stent strategy in the management of abdominal aortic aneurysms Ding, Yuan Zhongyou, Li Wentao, Jiang Yinci, Zhang Zhenze, Wang Yu, Chen Sci Rep Article Treating an abdominal aortic aneurysm (AAA) with a stent graft (SG) and a multilayer stent (MS) is a key technology in isolating flow fields. Clinically, dual stents (an SG in the proximal and an MS in the distal of AAA) are used for treatment of AAA, but only a few studies have examined the relationship between SG coverage and treatment effects. Through numerical simulation of the hemodynamics after SG and MS implantation, the SG coverage and position were simulated at 0% (0 mm), 25% (13.75 mm), 50% (27.5 mm), and 75% (41.25 mm). With increasing SG coverage, the pressure on the aneurysm sac wall and the flow of branch vessels gradually decreased, and the lower wall shear stress (WSS) gradually increased. The changes in pressure, lower WSS, and the mass flow rate of the branch vessels did not change significantly. The coverage of the SG has a nonsignificant effect on hemodynamics in the treatment of AAA; the implantation position need not be very precise. This research can provide theoretic support for clinicians’ decision-making. Nature Publishing Group UK 2018-11-05 /pmc/articles/PMC6218544/ /pubmed/30397213 http://dx.doi.org/10.1038/s41598-018-34354-2 Text en © The Author(s) 2018 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Article Ding, Yuan Zhongyou, Li Wentao, Jiang Yinci, Zhang Zhenze, Wang Yu, Chen Stent graft coverage of dual-stent strategy in the management of abdominal aortic aneurysms |
title | Stent graft coverage of dual-stent strategy in the management of abdominal aortic aneurysms |
title_full | Stent graft coverage of dual-stent strategy in the management of abdominal aortic aneurysms |
title_fullStr | Stent graft coverage of dual-stent strategy in the management of abdominal aortic aneurysms |
title_full_unstemmed | Stent graft coverage of dual-stent strategy in the management of abdominal aortic aneurysms |
title_short | Stent graft coverage of dual-stent strategy in the management of abdominal aortic aneurysms |
title_sort | stent graft coverage of dual-stent strategy in the management of abdominal aortic aneurysms |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6218544/ https://www.ncbi.nlm.nih.gov/pubmed/30397213 http://dx.doi.org/10.1038/s41598-018-34354-2 |
work_keys_str_mv | AT dingyuan stentgraftcoverageofdualstentstrategyinthemanagementofabdominalaorticaneurysms AT zhongyouli stentgraftcoverageofdualstentstrategyinthemanagementofabdominalaorticaneurysms AT wentaojiang stentgraftcoverageofdualstentstrategyinthemanagementofabdominalaorticaneurysms AT yincizhang stentgraftcoverageofdualstentstrategyinthemanagementofabdominalaorticaneurysms AT zhenzewang stentgraftcoverageofdualstentstrategyinthemanagementofabdominalaorticaneurysms AT yuchen stentgraftcoverageofdualstentstrategyinthemanagementofabdominalaorticaneurysms |