Adenosinergic Signaling Alters Natural Killer Cell Functional Responses

Adenosine is a potent immunosuppressive purine metabolite contributing to the pathogenesis of solid tumors. Extracellular adenosine signals on tumor-infiltrating NK cells to inhibit their proliferation, maturation, and cytotoxic function. Cytokine priming imparts upon NK cells distinct activation st...

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Detalles Bibliográficos
Autores principales: Chambers, Andrea M., Wang, Jiao, Lupo, Kyle B., Yu, Hao, Atallah Lanman, Nadia M., Matosevic, Sandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6218627/
https://www.ncbi.nlm.nih.gov/pubmed/30425720
http://dx.doi.org/10.3389/fimmu.2018.02533

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6218627/
https://www.ncbi.nlm.nih.gov/pubmed/30425720
http://dx.doi.org/10.3389/fimmu.2018.02533

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