Randomized, Double‐Blind, Placebo‐Controlled, Single Ascending Dose Trial of Synthetic Preimplantation Factor in Autoimmune Hepatitis

Preimplantation factor (PIF) is an evolutionary conserved peptide secreted by viable embryos which promotes maternal tolerance without immune suppression. Synthetic PIF (sPIF) replicates native peptide activity. The aim of this study was to conduct the first‐in‐human trial of the safety, tolerabilit...

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Detalles Bibliográficos
Autores principales: O’Brien, Christopher B., Barnea, Eytan R., Martin, Paul, Levy, Cynthia, Sharabi, Eden, Bhamidimarri, Kalyan R., Martin, Eric, Arosemena, Leopold, Schiff, Eugene R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6218676/
https://www.ncbi.nlm.nih.gov/pubmed/30411073
http://dx.doi.org/10.1002/hep4.1239

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6218676/
https://www.ncbi.nlm.nih.gov/pubmed/30411073
http://dx.doi.org/10.1002/hep4.1239

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