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Decrease in Intracellular Perforin Levels and IFN-γ Production in Human CD8(+) T Cell Line following Long-Term Exposure to Asbestos Fibers
Although the tumorigenicity of asbestos, which is thought to cause mesothelioma, has been clarified, its effect on antitumor immunity requires further investigation. We previously reported a decrease in the percentage of perforin(+) cells of stimulated CD8(+) lymphocytes derived from patients with m...
Autores principales: | Kumagai-Takei, Naoko, Nishimura, Yasumitsu, Matsuzaki, Hidenori, Lee, Suni, Yoshitome, Kei, Otsuki, Takemi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6218727/ https://www.ncbi.nlm.nih.gov/pubmed/30426024 http://dx.doi.org/10.1155/2018/4391731 |
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