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Evidence of Direct Toxicological Effects of Scorpion Venom on Central Nervous System in Tunisian Children

BACKGROUND: Severe scorpion envenomation can lead to severe neurological manifestations, which are an indicator of the severity of the scorpion sting. The direct action of scorpion venom on the central nervous system can explain partly these neurological disorders. METHODS AND FINDINGS: We report a...

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Autores principales: Bahloul, Mabrouk, Souissi, Basma, Turki, Olfa, Dlela, Mariem, Ben Mahfoudh, Khaireddine, Bouaziz, Mounir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6218758/
https://www.ncbi.nlm.nih.gov/pubmed/30425860
http://dx.doi.org/10.1155/2018/8304375
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author Bahloul, Mabrouk
Souissi, Basma
Turki, Olfa
Dlela, Mariem
Ben Mahfoudh, Khaireddine
Bouaziz, Mounir
author_facet Bahloul, Mabrouk
Souissi, Basma
Turki, Olfa
Dlela, Mariem
Ben Mahfoudh, Khaireddine
Bouaziz, Mounir
author_sort Bahloul, Mabrouk
collection PubMed
description BACKGROUND: Severe scorpion envenomation can lead to severe neurological manifestations, which are an indicator of the severity of the scorpion sting. The direct action of scorpion venom on the central nervous system can explain partly these neurological disorders. METHODS AND FINDINGS: We report a case of severe scorpion envenomation in 16-month-old boy with no pathological history admitted in ICU for severe scorpion envenomation. The result of cerebral MRI agrees with the hypothesis of direct action of scorpion venom on the central nervous system. Patient had improved; however, he has kept as neurological sequelae language disorders and blindness. The boy was discharged 21 days after ICU admission. CONCLUSION: Our observation confirms that severe scorpion envenomation can be complicated by severe neurological manifestations. Although one case report is not enough to conclude such important hypothesis regarding the direct effect of scorpion venom on central nervous system (especially that the age of patient is more than one year), our case agrees with this hypothesis.
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spelling pubmed-62187582018-11-13 Evidence of Direct Toxicological Effects of Scorpion Venom on Central Nervous System in Tunisian Children Bahloul, Mabrouk Souissi, Basma Turki, Olfa Dlela, Mariem Ben Mahfoudh, Khaireddine Bouaziz, Mounir Case Rep Crit Care Case Report BACKGROUND: Severe scorpion envenomation can lead to severe neurological manifestations, which are an indicator of the severity of the scorpion sting. The direct action of scorpion venom on the central nervous system can explain partly these neurological disorders. METHODS AND FINDINGS: We report a case of severe scorpion envenomation in 16-month-old boy with no pathological history admitted in ICU for severe scorpion envenomation. The result of cerebral MRI agrees with the hypothesis of direct action of scorpion venom on the central nervous system. Patient had improved; however, he has kept as neurological sequelae language disorders and blindness. The boy was discharged 21 days after ICU admission. CONCLUSION: Our observation confirms that severe scorpion envenomation can be complicated by severe neurological manifestations. Although one case report is not enough to conclude such important hypothesis regarding the direct effect of scorpion venom on central nervous system (especially that the age of patient is more than one year), our case agrees with this hypothesis. Hindawi 2018-10-23 /pmc/articles/PMC6218758/ /pubmed/30425860 http://dx.doi.org/10.1155/2018/8304375 Text en Copyright © 2018 Mabrouk Bahloul et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Bahloul, Mabrouk
Souissi, Basma
Turki, Olfa
Dlela, Mariem
Ben Mahfoudh, Khaireddine
Bouaziz, Mounir
Evidence of Direct Toxicological Effects of Scorpion Venom on Central Nervous System in Tunisian Children
title Evidence of Direct Toxicological Effects of Scorpion Venom on Central Nervous System in Tunisian Children
title_full Evidence of Direct Toxicological Effects of Scorpion Venom on Central Nervous System in Tunisian Children
title_fullStr Evidence of Direct Toxicological Effects of Scorpion Venom on Central Nervous System in Tunisian Children
title_full_unstemmed Evidence of Direct Toxicological Effects of Scorpion Venom on Central Nervous System in Tunisian Children
title_short Evidence of Direct Toxicological Effects of Scorpion Venom on Central Nervous System in Tunisian Children
title_sort evidence of direct toxicological effects of scorpion venom on central nervous system in tunisian children
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6218758/
https://www.ncbi.nlm.nih.gov/pubmed/30425860
http://dx.doi.org/10.1155/2018/8304375
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