The Malaria-Protective Human Glycophorin Structural Variant DUP4 Shows Somatic Mosaicism and Association with Hemoglobin Levels

Glycophorin A and glycophorin B are red blood cell surface proteins and are both receptors for the parasite Plasmodium falciparum, which is the principal cause of malaria in sub-Saharan Africa. DUP4 is a complex structural genomic variant that carries extra copies of a glycophorin A-glycophorin B fu...

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Detalles Bibliográficos
Autores principales: Algady, Walid, Louzada, Sandra, Carpenter, Danielle, Brajer, Paulina, Färnert, Anna, Rooth, Ingegerd, Ngasala, Billy, Yang, Fengtang, Shaw, Marie-Anne, Hollox, Edward J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6218809/
https://www.ncbi.nlm.nih.gov/pubmed/30388403
http://dx.doi.org/10.1016/j.ajhg.2018.10.008

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