Cargando…

Investigate the mechanisms of Chinese medicine Fuzhengkangai towards EGFR mutation-positive lung adenocarcinomas by network pharmacology

BACKGROUND: Chinese traditional herbal medicine Fuzhengkangai (FZKA) formulation combination with gefitinib can overcome drug resistance and improve the prognosis of lung adenocarcinoma patients. However, the pharmacological and molecular mechanisms underlying the active ingredients, potential targe...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bing, Zhitong, Cheng, Zhiyuan, Shi, Danfeng, Liu, Xinkui, Tian, Jinhui, Yao, Xiaojun, Zhang, Jingyun, Wang, Yongfeng, Yang, Kehu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6218988/ https://www.ncbi.nlm.nih.gov/pubmed/30400936 http://dx.doi.org/10.1186/s12906-018-2347-x

Ejemplares similares

Comprehensive assessment gene signatures for clear cell renal cell carcinoma prognosis
por: Chang, Peng, et al.
Publicado: (2018)

Novel Model for Comprehensive Assessment of Robust Prognostic Gene Signature in Ovarian Cancer Across Different Independent Datasets
por: Bing, Zhitong, et al.
Publicado: (2019)

A bioinformatics investigation into the pharmacological mechanisms of the effect of the Yinchenhao decoction on hepatitis C based on network pharmacology
por: Zhang, Jingyuan, et al.
Publicado: (2020)

Identification of robust diagnostic and prognostic gene signatures in different grades of gliomas: a retrospective study
por: Liu, Jieting, et al.
Publicado: (2021)

Top-100 Most Cited Publications Concerning Network Pharmacology: A Bibliometric Analysis
por: Lu, Cuncun, et al.
Publicado: (2019)

Integrative Gene Expression Profiling Analysis to Investigate Potential Prognostic Biomarkers for Colorectal Cancer
por: Liu, Xinkui, et al.
Publicado: (2020)

Identification of Potential Key Genes Associated With the Pathogenesis and Prognosis of Gastric Cancer Based on Integrated Bioinformatics Analysis
por: Liu, Xinkui, et al.
Publicado: (2018)

Computational Insight Into the Small Molecule Intervening PD-L1 Dimerization and the Potential Structure-Activity Relationship
por: Shi, Danfeng, et al.
Publicado: (2019)

Investigating the multi-target pharmacological mechanism of danhong injection acting on unstable angina by combined network pharmacology and molecular docking
por: Guo, Siyu, et al.
Publicado: (2020)

Network Pharmacology-Based Approach to Investigate the Mechanisms of Hedyotis diffusa Willd. in the Treatment of Gastric Cancer
por: Liu, Xinkui, et al.
Publicado: (2018)

The Use of Traditional Chinese Medicine in Relieving EGFR-TKI-Associated Diarrhea Based on Network Pharmacology and Data Mining
por: Hu, Shuaihang, et al.
Publicado: (2021)

Individualized Medication of Voriconazole: A Practice Guideline of the Division of Therapeutic Drug Monitoring, Chinese Pharmacological Society
por: Chen, Ken, et al.
Publicado: (2018)

Immunogenicity of Del19 EGFR mutations in Chinese patients affected by lung adenocarcinoma
por: Pan, Deng, et al.
Publicado: (2019)

Systems Pharmacology for Investigation of the Mechanisms of Action of Traditional Chinese Medicine in Drug Discovery
por: Zhang, Wenjuan, et al.
Publicado: (2019)

Prognostic implications of immunohistochemistry markers for EGFR-TKI therapy in Chinese patients with advanced lung adenocarcinoma harboring EGFR mutations
por: Zhang, Ruiguang, et al.
Publicado: (2016)

Methodological Reporting of Randomized Trials in Five Leading Chinese Nursing Journals
por: Shi, Chunhu, et al.
Publicado: (2014)

The Efficacy of Traditional Chinese Herbal Medicine in the Treatment of EGFR Mutated Stage IV Pulmonary Adenocarcinoma Patients Who Received First-Line EGFR-TKI Treatment
por: Hung, Hsiu-Ying, et al.
Publicado: (2016)

Applications of Network Pharmacology in Traditional Chinese Medicine Research
por: Zhou, Zhuchen, et al.
Publicado: (2020)

A bioinformatics investigation into the pharmacological mechanisms of javanica oil emulsion injection in non-small cell lung cancer based on network pharmacology methodologies
por: Ni, Mengwei, et al.
Publicado: (2020)

A network pharmacology-based investigation of emodin against pancreatic adenocarcinoma
por: Shi, Xueying, et al.
Publicado: (2023)

Investigation of the Mechanism of Traditional Chinese Medicines in Angiogenesis through Network Pharmacology and Data Mining
por: Yun, Wingyan, et al.
Publicado: (2021)

Chinese Medicine as an Adjunctive Treatment for Gastric Cancer: Methodological Investigation of meta-Analyses and Evidence Map
por: Lu, Cuncun, et al.
Publicado: (2022)

Chinese Herbal Medicine Combined With EGFR-TKI in EGFR Mutation-Positive Advanced Pulmonary Adenocarcinoma (CATLA): A Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial
por: Jiao, Lijing, et al.
Publicado: (2019)

Pharmacological interventions for preventing post-operative atrial fibrillation in patients undergoing cardiac surgery: a network meta-analysis protocol
por: Wang, Xiaoqin, et al.
Publicado: (2017)

A systematic review of the research progress of traditional Chinese medicine against pulmonary fibrosis: from a pharmacological perspective
por: Qin, Shanbo, et al.
Publicado: (2023)

Predicting EGFR mutation status in lung adenocarcinoma on computed tomography image using deep learning
por: Wang, Shuo, et al.
Publicado: (2019)

Toward automatic prediction of EGFR mutation status in pulmonary adenocarcinoma with 3D deep learning
por: Zhao, Wei, et al.
Publicado: (2019)

Thick-wall cavity predicts worse progression-free survival in lung adenocarcinoma treated with first-line EGFR-TKIs
por: Zhou, Fei, et al.
Publicado: (2018)

Comprehensive analysis of immune-related genes associated with the microenvironment of patients with unexplained infertility
por: Wang, Caiyun, et al.
Publicado: (2023)

Efficacy and safety of afatinib in a Chinese population with advanced lung adenocarcinoma with sensitive EGFR mutations
por: Wang, Shouzheng, et al.
Publicado: (2019)

Clinicopathologic and molecular characteristics of Chinese lung adenocarcinoma patients with EGFR exon 20 insertion mutations
por: Wang, Lifeng, et al.
Publicado: (2022)

Combining Chemical Profiling and Network Analysis to Investigate the Pharmacology of Complex Prescriptions in Traditional Chinese Medicine
por: Suo, Tongchuan, et al.
Publicado: (2017)

Network Pharmacology in Traditional Chinese Medicine
por: Li, Shao, et al.
Publicado: (2014)

Traditional Chinese Medicine and Clinical Pharmacology
por: Marshall, Anita Chen
Publicado: (2020)

A bioinformatics investigation into molecular mechanism of Yinzhihuang granules for treating hepatitis B by network pharmacology and molecular docking verification
por: Zhang, Jingyuan, et al.
Publicado: (2020)

Network Pharmacology: A New Approach for Chinese Herbal Medicine Research
por: Zhang, Gui-biao, et al.
Publicado: (2013)

Revealing inhibition difference between PFI-2 enantiomers against SETD7 by molecular dynamics simulations, binding free energy calculations and unbinding pathway analysis
por: Niu, Yuzhen, et al.
Publicado: (2017)

Heterogeneity of tumor immune microenvironment of EGFR/ALK-positive tumors versus EGFR/ALK-negative tumors in resected brain metastases from lung adenocarcinoma
por: Xiao, Gang, et al.
Publicado: (2023)

Investigation on the mechanisms of guiqi huoxue capsule for treating cervical spondylosis based on network pharmacology and molecular docking
por: Liu, Yingying, et al.
Publicado: (2021)

Chinese Herbal Medicines Attenuate Acute Pancreatitis: Pharmacological Activities and Mechanisms
por: Xiang, Hong, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_kih9h3mmpusdt5p03i4l03sdtg