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Analysis and correction of compositional bias in sparse sequencing count data

BACKGROUND: Count data derived from high-throughput deoxy-ribonucliec acid (DNA) sequencing is frequently used in quantitative molecular assays. Due to properties inherent to the sequencing process, unnormalized count data is compositional, measuring relative and not absolute abundances of the assay...

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Detalles Bibliográficos
Autores principales:	Kumar, M. Senthil, Slud, Eric V., Okrah, Kwame, Hicks, Stephanie C., Hannenhalli, Sridhar, Corrada Bravo, Héctor
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Methodology Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219007/ https://www.ncbi.nlm.nih.gov/pubmed/30400812 http://dx.doi.org/10.1186/s12864-018-5160-5

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