M3 muscarinic acetylcholine receptors regulate epithelial–mesenchymal transition, perineural invasion, and migration/metastasis in cholangiocarcinoma through the AKT pathway

BACKGROUND: Cholangiocarcinoma is a highly malignant tumor type that is not sensitive to radiotherapy or chemotherapy due to aggressive perineural invasion and metastasis. Unfortunately, the mechanisms underlying these processes and the signaling factors involved are largely unknown. In this study,...

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Detalles Bibliográficos
Autores principales: Feng, Yujie, Hu, Xiao, Liu, Guangwei, Lu, Lianfang, Zhao, Wei, Shen, Fangzhen, Ma, Kai, Sun, Chuandong, Zhu, Chengzhan, Zhang, Bingyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Primary Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219094/
https://www.ncbi.nlm.nih.gov/pubmed/30450012
http://dx.doi.org/10.1186/s12935-018-0667-z

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