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Insecticide resistance in Anopheles gambiae from the northern Democratic Republic of Congo, with extreme knockdown resistance (kdr) mutation frequencies revealed by a new diagnostic assay
BACKGROUND: Mutations in the voltage-gated sodium channel at codon 1014 confer knock-down resistance (kdr) to pyrethroids in a wide range of insects. Anopheles gambiae exhibits two mutant alleles at codon 1014, serine and phenylalanine; and both are now widespread across Africa. Existing screening m...
Autores principales: | Lynd, Amy, Oruni, Ambrose, van’t Hof, Arjen E., Morgan, John C., Naego, Leon Bwazumo, Pipini, Dimitra, O’Kines, Kevin A., Bobanga, Thierry L., Donnelly, Martin J., Weetman, David |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219172/ https://www.ncbi.nlm.nih.gov/pubmed/30400885 http://dx.doi.org/10.1186/s12936-018-2561-5 |
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