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DNA methylation and de-methylation using hybrid site-targeting proteins

DNA methylation plays important roles in determining cellular identity, disease, and environmental responses, but little is known about the mechanisms that drive methylation changes during cellular differentiation and tumorigenesis. Meanwhile, the causal relationship between DNA methylation and tran...

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Detalles Bibliográficos
Autores principales:	Lei, Yong, Huang, Yung-Hsin, Goodell, Margaret A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219187/ https://www.ncbi.nlm.nih.gov/pubmed/30400938 http://dx.doi.org/10.1186/s13059-018-1566-2

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