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Nitrosative stress in human spermatozoa causes cell death characterized by induction of mitochondrial permeability transition-driven necrosis
Peroxynitrite is a highly reactive nitrogen species and a potent inducer of apoptosis and necrosis in somatic cells. Peroxynitrite-induced nitrosative stress has emerged as a major cause of impaired sperm function; however, its ability to trigger cell death has not been described in human spermatozo...
Autores principales: | Uribe, Pamela, Cabrillana, María E, Fornés, Miguel W, Treulen, Favián, Boguen, Rodrigo, Isachenko, Vladimir, Isachenko, Evgenia, Sánchez, Raúl, Villegas, Juana V |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219306/ https://www.ncbi.nlm.nih.gov/pubmed/29956685 http://dx.doi.org/10.4103/aja.aja_29_18 |
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