Outcomes of pterygium surgery-glue versus autologous blood versus sutures for graft fixation-an analysis

AIM: The aim of this study is to compare the surgical outcomes of pterygium excision with conjunctival autograft using sutures, fibrin glue (tisseel), and autologous blood for the management of primary pterygium. PATIENTS AND METHODS: A retrospective study done in 681 eyes with primary nasal pterygium. Excision of the pterygium was performed followed by closure of the bare sclera with conjunctival autograft using interrupted 10-0 monofilament nylon sutures in 173 eyes (Group 1), fibrin glue (tisseel-baxter healthcare corporation, westlake village, ca-91362 USA) in 351 eyes (Group 2), and autologous blood in 157 eyes (Group 3). Patients were followed up for a period of 5–52 months. During follow-up, graft-related complications such as recurrence, graft loss, graft retraction, granuloma if any were noted and compared among the three groups. RESULTS: A total of 681 eyes who had primary nasal pterygium were included in this study. Pterygium excision with conjunctival autograft was performed using 10-0 monofilament nylon interrupted sutures in 173 eyes (25.4%), tisseel fibrin glue in 351 eyes (51.54%), and autologous blood in 157 (23.05%) eyes. The mean duration of follow-up was 5–52 months. The overall recurrence rate was 2.9% (20 eyes). In Group 1, recurrence was seen in 5 eyes (2.89%), in Group 2, it was seen in 7 eyes (1.99%) and in Group 3, 8 eyes (5.10%). However, the recurrence rate was not significant (P = 0.160). The rate of graft retraction in the 3 study groups were 12 eyes (6.94%), 10 eyes (2.85%), and 56 eyes (35.67%) with a significant P < 0.001. Granuloma was seen in 2 eyes (1.16%), in Group 1, and in 1 eye (0.64%) in Group 3. Graft loss was seen in 3 eyes (1.73%), 4 eyes (1.14%), 6 eyes (3.82%) in Group 1, 2, and 3, respectively. CONCLUSION: The outcomes of the three most commonly performed surgical technique of conjunctival autograft fixation has shown us that all three techniques are equally comparable and can be offered to our patients with equally good results.