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Allergen Exposure in Lymphopenic Fas-Deficient Mice Results in Persistent Eosinophilia Due to Defects in Resolution of Inflammation
Asthma is characterized by chronic airway type-2 inflammation and eosinophilia, yet the mechanisms involved in chronic, non-resolving inflammation remain poorly defined. Previously, our group has found that when Rag-deficient mice were reconstituted with Fas-deficient B6 LPR T cells and sensitized a...
Autores principales: | Ferreira, Caroline M., Williams, Jesse W., Tong, Jiankun, Rayon, Crystal, Blaine, Kelly M., Sperling, Anne I. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219400/ https://www.ncbi.nlm.nih.gov/pubmed/30425708 http://dx.doi.org/10.3389/fimmu.2018.02395 |
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