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Allergen Exposure in Lymphopenic Fas-Deficient Mice Results in Persistent Eosinophilia Due to Defects in Resolution of Inflammation

Asthma is characterized by chronic airway type-2 inflammation and eosinophilia, yet the mechanisms involved in chronic, non-resolving inflammation remain poorly defined. Previously, our group has found that when Rag-deficient mice were reconstituted with Fas-deficient B6 LPR T cells and sensitized a...

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Detalles Bibliográficos
Autores principales: Ferreira, Caroline M., Williams, Jesse W., Tong, Jiankun, Rayon, Crystal, Blaine, Kelly M., Sperling, Anne I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219400/
https://www.ncbi.nlm.nih.gov/pubmed/30425708
http://dx.doi.org/10.3389/fimmu.2018.02395

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