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Memory inflation following adenoviral vaccination depends on IL-21
Cytomegalovirus (CMV) and non-replicating adenoviral vectors can induce expanded, sustained effector-memory CD8(+) T-cell responses, termed “memory inflation”. During murine CMV (MCMV) infection, CD4(+) Tcells maintain inflationary virus-specific CD8(+) T-cell responses via IL-2 but not IL-21. Adeno...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier Science
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219444/ https://www.ncbi.nlm.nih.gov/pubmed/30279090 http://dx.doi.org/10.1016/j.vaccine.2018.09.061 |