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Structural basis of Gip1 for cytosolic sequestration of G protein in wide-range chemotaxis

G protein interacting protein 1 (Gip1) binds and sequesters heterotrimeric G proteins in the cytosolic pool, thus regulating G protein-coupled receptor (GPCR) signalling for eukaryotic chemotaxis. Here, we report the underlying structural basis of Gip1 function. The crystal structure reveals that th...

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Detalles Bibliográficos
Autores principales:	Miyagawa, Takero, Koteishi, Hiroyasu, Kamimura, Yoichiro, Miyanaga, Yukihiro, Takeshita, Kohei, Nakagawa, Atsushi, Ueda, Masahiro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219514/ https://www.ncbi.nlm.nih.gov/pubmed/30401901 http://dx.doi.org/10.1038/s41467-018-07035-x

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