Epigenetic profiling for the molecular classification of metastatic brain tumors

Optimal treatment of brain metastases is often hindered by limitations in diagnostic capabilities. To meet this challenge, here we profile DNA methylomes of the three most frequent types of brain metastases: melanoma, breast, and lung cancers (n = 96). Using supervised machine learning and integrati...

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Detalles Bibliográficos
Autores principales: Orozco, Javier I. J., Knijnenburg, Theo A., Manughian-Peter, Ayla O., Salomon, Matthew P., Barkhoudarian, Garni, Jalas, John R., Wilmott, James S., Hothi, Parvinder, Wang, Xiaowen, Takasumi, Yuki, Buckland, Michael E., Thompson, John F., Long, Georgina V., Cobbs, Charles S., Shmulevich, Ilya, Kelly, Daniel F., Scolyer, Richard A., Hoon, Dave S. B., Marzese, Diego M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219520/
https://www.ncbi.nlm.nih.gov/pubmed/30401823
http://dx.doi.org/10.1038/s41467-018-06715-y

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