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Temporal changes of Sall4 lineage contribution in developing embryos and the contribution of Sall4-lineages to postnatal germ cells in mice

Mutations in the SALL4 gene cause human syndromes with defects in multiple organs. Sall4 expression declines rapidly in post-gastrulation mouse embryos, and our understanding of the requirement of Sall4 in animal development is still limited. To assess the contributions of Sall4 expressing cells to...

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Detalles Bibliográficos
Autores principales: Tahara, Naoyuki, Kawakami, Hiroko, Zhang, Teng, Zarkower, David, Kawakami, Yasuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219540/
https://www.ncbi.nlm.nih.gov/pubmed/30401915
http://dx.doi.org/10.1038/s41598-018-34745-5