In Silico Study Reveals How E64 Approaches, Binds to, and Inhibits Falcipain-2 of Plasmodium falciparum that Causes Malaria in Humans

Plasmodium falciparum malaria, which degrades haemoglobin through falcipain-2 (FP2), is a serious disease killing 445 thousand people annually. Since the P. falciparum’s survival in humans depends on its ability to degrade human’s haemoglobin, stoppage or hindrance of FP2 has antimalarial effects. T...

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Detalles Bibliográficos
Autor principal: Salawu, Emmanuel Oluwatobi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219542/
https://www.ncbi.nlm.nih.gov/pubmed/30401806
http://dx.doi.org/10.1038/s41598-018-34622-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219542/
https://www.ncbi.nlm.nih.gov/pubmed/30401806
http://dx.doi.org/10.1038/s41598-018-34622-1

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