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Down-regulation of AR splice variants through XPO1 suppression contributes to the inhibition of prostate cancer progression

Emerging studies have shown that the expression of AR splice variants (ARv) lacking ligand-binding domain is associated with castrate-resistant prostate cancer (CRPC) and higher risk of tumor metastasis and recurrence. Nuclear export protein XPO1 regulates the nuclear localization of many proteins i...

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Detalles Bibliográficos
Autores principales:	Aboukameel, Amro, Muqbil, Irfana, Baloglu, Erkan, Senapedis, William, Landesman, Yosef, Argueta, Christian, Kauffman, Michael, Chang, Hua, Kashyap, Trinayan, Shacham, Sharon, Neggers, Jasper E., Daelemans, Dirk, Heath, Elisabeth I., Azmi, Asfar S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2018
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219671/ https://www.ncbi.nlm.nih.gov/pubmed/30450161 http://dx.doi.org/10.18632/oncotarget.26239

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