Nebulin increases thin filament stiffness and force per cross-bridge in slow-twitch soleus muscle fibers

Nebulin (Neb) is associated with the thin filament in skeletal muscle cells, but its functions are not well understood. For this goal, we study skinned slow-twitch soleus muscle fibers from wild-type (Neb(+)) and conditional Neb knockout (Neb(−)) mice. We characterize cross-bridge (CB) kinetics and...

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Detalles Bibliográficos
Autores principales: Kawai, Masataka, Karam, Tarek S., Kolb, Justin, Wang, Li, Granzier, Henk L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219688/
https://www.ncbi.nlm.nih.gov/pubmed/30301869
http://dx.doi.org/10.1085/jgp.201812104

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219688/
https://www.ncbi.nlm.nih.gov/pubmed/30301869
http://dx.doi.org/10.1085/jgp.201812104

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