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Nebulin increases thin filament stiffness and force per cross-bridge in slow-twitch soleus muscle fibers
Nebulin (Neb) is associated with the thin filament in skeletal muscle cells, but its functions are not well understood. For this goal, we study skinned slow-twitch soleus muscle fibers from wild-type (Neb(+)) and conditional Neb knockout (Neb(−)) mice. We characterize cross-bridge (CB) kinetics and...
Autores principales: | Kawai, Masataka, Karam, Tarek S., Kolb, Justin, Wang, Li, Granzier, Henk L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219688/ https://www.ncbi.nlm.nih.gov/pubmed/30301869 http://dx.doi.org/10.1085/jgp.201812104 |
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