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Kinetic properties of persistent Na(+) current orchestrate oscillatory bursting in respiratory neurons
The rhythmic pattern of breathing depends on the pre-Bötzinger complex (preBötC) in the brainstem, a vital circuit that contains a population of neurons with intrinsic oscillatory bursting behavior. Here, we investigate the specific kinetic properties that enable voltage-gated sodium channels to est...
Autores principales: | Yamanishi, Tadashi, Koizumi, Hidehiko, Navarro, Marco A., Milescu, Lorin S., Smith, Jeffrey C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219691/ https://www.ncbi.nlm.nih.gov/pubmed/30301870 http://dx.doi.org/10.1085/jgp.201812100 |
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