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A hypothetical molecular mechanism for TRPV1 activation that invokes rotation of an S6 asparagine
The transient receptor potential channel vanilloid type 1 (TRPV1) is activated by a variety of endogenous and exogenous stimuli and is involved in nociception and body temperature regulation. Although the structure of TRPV1 has been experimentally determined in both the closed and open states, very...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Rockefeller University Press
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219692/ https://www.ncbi.nlm.nih.gov/pubmed/30333107 http://dx.doi.org/10.1085/jgp.201812124 |