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A hypothetical molecular mechanism for TRPV1 activation that invokes rotation of an S6 asparagine

The transient receptor potential channel vanilloid type 1 (TRPV1) is activated by a variety of endogenous and exogenous stimuli and is involved in nociception and body temperature regulation. Although the structure of TRPV1 has been experimentally determined in both the closed and open states, very...

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Detalles Bibliográficos
Autores principales: Kasimova, Marina A., Yazici, Aysenur Torun, Yudin, Yevgen, Granata, Daniele, Klein, Michael L., Rohacs, Tibor, Carnevale, Vincenzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219692/
https://www.ncbi.nlm.nih.gov/pubmed/30333107
http://dx.doi.org/10.1085/jgp.201812124

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