Modulating apical–basal polarity by building and deconstructing a Yurt

Cell polarity is regulated by protein networks in the apical and basolateral domains that repress one another by mutually antagonistic interactions. Gamblin et al. (2018. J. Cell Biol. https://doi.org/10.1083/jcb.201803099) reveal that apical Crumbs is antagonized by oligomerization of basolateral Y...

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Detalles Bibliográficos
Autores principales: Perez-Vale, Kia Z., Peifer, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2018
Materias:
Commentaries
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219707/
https://www.ncbi.nlm.nih.gov/pubmed/30361467
http://dx.doi.org/10.1083/jcb.201810059
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author Perez-Vale, Kia Z.
Peifer, Mark
author_facet Perez-Vale, Kia Z.
Peifer, Mark
author_sort Perez-Vale, Kia Z.
collection PubMed
description Cell polarity is regulated by protein networks in the apical and basolateral domains that repress one another by mutually antagonistic interactions. Gamblin et al. (2018. J. Cell Biol. https://doi.org/10.1083/jcb.201803099) reveal that apical Crumbs is antagonized by oligomerization of basolateral Yurt, while Yurt oligomerization is in turn negatively regulated by the apical kinase aPKC.
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spelling pubmed-62197072019-05-05 Modulating apical–basal polarity by building and deconstructing a Yurt Perez-Vale, Kia Z. Peifer, Mark J Cell Biol Commentaries Cell polarity is regulated by protein networks in the apical and basolateral domains that repress one another by mutually antagonistic interactions. Gamblin et al. (2018. J. Cell Biol. https://doi.org/10.1083/jcb.201803099) reveal that apical Crumbs is antagonized by oligomerization of basolateral Yurt, while Yurt oligomerization is in turn negatively regulated by the apical kinase aPKC. Rockefeller University Press 2018-11-05 /pmc/articles/PMC6219707/ /pubmed/30361467 http://dx.doi.org/10.1083/jcb.201810059 Text en © 2018 Perez-Vale and Peifer http://www.rupress.org/terms/https://creativecommons.org/licenses/by-nc-sa/4.0/This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms/). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 International license, as described at https://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Commentaries
Perez-Vale, Kia Z.
Peifer, Mark
Modulating apical–basal polarity by building and deconstructing a Yurt
title Modulating apical–basal polarity by building and deconstructing a Yurt
title_full Modulating apical–basal polarity by building and deconstructing a Yurt
title_fullStr Modulating apical–basal polarity by building and deconstructing a Yurt
title_full_unstemmed Modulating apical–basal polarity by building and deconstructing a Yurt
title_short Modulating apical–basal polarity by building and deconstructing a Yurt
title_sort modulating apical–basal polarity by building and deconstructing a yurt
topic Commentaries
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219707/
https://www.ncbi.nlm.nih.gov/pubmed/30361467
http://dx.doi.org/10.1083/jcb.201810059
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