Mapping 3D genome organization relative to nuclear compartments using TSA-Seq as a cytological ruler

While nuclear compartmentalization is an essential feature of three-dimensional genome organization, no genomic method exists for measuring chromosome distances to defined nuclear structures. In this study, we describe TSA-Seq, a new mapping method capable of providing a “cytological ruler” for esti...

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Detalles Bibliográficos
Autores principales: Chen, Yu, Zhang, Yang, Wang, Yuchuan, Zhang, Liguo, Brinkman, Eva K., Adam, Stephen A., Goldman, Robert, van Steensel, Bas, Ma, Jian, Belmont, Andrew S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219710/
https://www.ncbi.nlm.nih.gov/pubmed/30154186
http://dx.doi.org/10.1083/jcb.201807108

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