Cargando…
β-Catenin is a pH sensor with decreased stability at higher intracellular pH
β-Catenin functions as an adherens junction protein for cell–cell adhesion and as a signaling protein. β-catenin function is dependent on its stability, which is regulated by protein–protein interactions that stabilize β-catenin or target it for proteasome-mediated degradation. In this study, we sho...
Autores principales: | White, Katharine A., Grillo-Hill, Bree K., Esquivel, Mario, Peralta, Jobelle, Bui, Vivian N., Chire, Ismahan, Barber, Diane L. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219716/ https://www.ncbi.nlm.nih.gov/pubmed/30315137 http://dx.doi.org/10.1083/jcb.201712041 |
Ejemplares similares
-
Oncogenic β-catenin mutations evade pH-regulated degradation
por: Grillo-Hill, Bree K., et al.
Publicado: (2019) -
Increased intracellular pH is necessary for adult epithelial and embryonic stem cell differentiation
por: Ulmschneider, Bryne, et al.
Publicado: (2016) -
CO(2)chemotransduction in central neurons: role of intracellular pH (pH(i)) and extracellular pH (pH(o))
por: Putnam, RW
Publicado: (2001) -
Intracellular pH Regulates Cancer and Stem Cell Behaviors: A Protein Dynamics Perspective
por: Liu, Yi, et al.
Publicado: (2020) -
Illumination of the Spatial Order of Intracellular pH by Genetically Encoded pH-Sensitive Sensors
por: Benčina, Mojca
Publicado: (2013)