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Mycobacterium tuberculosis–induced IFN-β production requires cytosolic DNA and RNA sensing pathways

RNA sensing pathways are key elements in a host immune response to viral pathogens, but little is known of their importance during bacterial infections. We found that Mycobacterium tuberculosis (M.tb) actively releases RNA into the macrophage cytosol using the mycobacterial SecA2 and ESX-1 secretion...

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Detalles Bibliográficos
Autores principales:	Cheng, Yong, Schorey, Jeffrey S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Rockefeller University Press 2018
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219742/ https://www.ncbi.nlm.nih.gov/pubmed/30337468 http://dx.doi.org/10.1084/jem.20180508

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