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Kinetics of adult hematopoietic stem cell differentiation in vivo

Adult hematopoiesis has been studied in terms of progenitor differentiation potentials, whereas its kinetics in vivo is poorly understood. We combined inducible lineage tracing of endogenous adult hematopoietic stem cells (HSCs) with flow cytometry and single-cell RNA sequencing to characterize earl...

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Detalles Bibliográficos
Autores principales: Upadhaya, Samik, Sawai, Catherine M., Papalexi, Efthymia, Rashidfarrokhi, Ali, Jang, Geunhyo, Chattopadhyay, Pratip, Satija, Rahul, Reizis, Boris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219744/
https://www.ncbi.nlm.nih.gov/pubmed/30291161
http://dx.doi.org/10.1084/jem.20180136